The greatest magnitude possible is just short of 50%. That occurs when a number just smaller than 15 is rounded down to 10.
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Improper calibration of the measuring instrument. If the measuring instrument is not at zero prior to measuring the object you will get a systematic error which, is a value either always higher or always lower then the actual value of the object.
The standard error.
A combination of factors increase the risk of a Type 1 error. Giving the wrong amount or wrong diagnosis for a wrong drug would certainly increase an error.
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A systematic error. This may arise because the measuring instrument is not properly calibrated or because there is a bias in recording the results.