It is not completely clear. Other signs were used for the negative sign, such as the letter m for minus. In fact, in 1484 Chuquet used the m for minus.
I will provide a great link with lots more info on the history of negative numbers.
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The ones with the + sign are positive. The ones with the - sign are negative.
negative
You get a negative.
(The product of 33 negative numbers) x (2 positive numbers) = (negative sign) x (positive sign) = negative sign
negative*negative=positive negative/positive=negative negative\negative=positve negative-positive=change the sign to a plus and then change the number after the sign and get your answer negative +positive=which ever numbr is bigger minus positive+positive=positive