In representing large numbers, English texts use commas (or spaces) to separate each group of three digits. This is almost always done for numbers of six or more digits, and optionally for five (or even four) digits. This makes it easier to read the number without having to count how many place holders there are in the number as a whole.
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I do not use commas.
Generally you use commas to define triplets of numbers (from the right). so 300698 = 300,698
Scientists? It's handy for writing out any large numbers...
It is easier to write 2.3 * 10-9 than to write 0.0000000023 ■
An advantage of using the scientific notation is that scientists have to use large and small numbers and this helps them by showing the number in a smaller way.