If the cell has a simple geometric shape, there are formulae that can be used. Otherwise you need to measure the surface area and the volume.
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As cell volume increases, the ratio of cell surface area to cell volume decreases. This is because the surface area increases by a square factor while the volume increases by a cube factor. A higher surface area to volume ratio is more favorable for efficient nutrient exchange and waste removal in cells.
The cell's ratio of surface area to volume would decrease. However, this scenario is extremely unlikely.
they have a greater surface-to-volume ratio
cell division
The surface area to volume ratio of cells must be compared to explain why almost all cells are small. As cells grow larger, their volume increases faster than their surface area, leading to inefficiencies in nutrient and waste exchange. Smaller cells have a higher surface area to volume ratio, allowing for more efficient cellular processes.