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No; for example, 14 ends with 4 but is not divisible by 4. One trick for determining if a large number is divisible by 4 is only look at the last 2 digits. If that number is divisible by 4, so is the entire number. For example, 147,328,120 is divisible by 4 because 20 is divisible by 4. But 483,394,399 is not because 99 is not divisible by 4.

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