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The question, as posed cannot be answered because you have not stated the units for the half-life. Some things have half lives of millions of years while others have half-lives measured in micro-seconds. Fortunately, Wikipedia came to my rescue and the half-life is 1600 years (approx).

The answer is approx 4.3 grams.

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Q: How many grams of radium-226 will remain from 5 grams after 365 years if the half life of radium 226 is 1600?
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