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The CH50 complement assay measures the activation of the complement system, which involves a immune response that is activated when the body encounters a foreign particle or substance; and is to test and monitor patients for diseases.

Increased complement activation levels can mean a possibility of cancer, or infections.

Decreased complement activity levels can mean a possiblity of immune/genetic deficiencies or diseases, such as kidney transplant rejections or improper functioning of the kidney or liver.

The following are normal levels:
* Total blood complement level: 41 to 90 hemolytic units
* C1 level: 16 to 33 mg/dL
* C3 levels:
o Males: 88 to 252 mg/dL
o Females: 88 to 206 mg/dL
* C4 levels:
o Males: 12 to 72 mg/dL
o Females: 13 to 75 mg/dL
Note: mg/dL = milligrams per deciliter.

Please note that the above information, including normal levels, is from personal knowledge and sources available on the internet. This is by no means a professional response; and the above is not sufficient to make a self-diagnosis. For exact levels and diagnosis, you should consult your doctor.

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Q: What does it mean if CH50 complement assay is higher than the expected range?
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