Assuming you meant the largest 3 digit number without repetition:
Largest 4 digit without repetition = 9876
Largest 3 digit = 987
⇒ difference = 9876 - 987 = 8889
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With repetition, there are 86 ( = 262144) such numbers. Without repetition, there are still 8!/2! = 20160.
you wil have to figure it out, is it your homework?
With repetition, 94 = 6561. Without repetition, 9*8*7*6 = 3024.
The difference between a hypothesis and a conjecture is that a hypothesis is something investigated or accepted as highly probable in the light established facts and a conjecture is the formation or expression of an opinion or theory without sufficient evidence for proof.