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Not at all. The nearest one to me is US90. It turns out, though, that the odd-numbered interstates run north-south, while the even-numbered interstates run east-west.
Odd numbers run Noth to south and begin in the West. Thus 25 is West of 35. Even numbers run East to West and begin in the South. Thus 40 is South of 80.
horizontal
Left to right
they go up and down
Odd numbered interstates run north and south. Even numbered interstates run east and west
Not at all. The nearest one to me is US90. It turns out, though, that the odd-numbered interstates run north-south, while the even-numbered interstates run east-west.
West to East or East to West
Odd numbered one and two digit interstates usually run north and south, although I-69 north of Lansing is signed as east-west. Three digit interstates are auxiliary routes and are therefore based on the direction they are going. For example, Interstate 35 itself goes north-south, but I-435 goes east-west, then turns and becomes north-south, then becomes east-west again, completing it's beltway in that fashion, intersecting I-35 twice (once in the north and once in the south).
North and south
north to south
Even number routes, such as I-90, run primarily east/west. Odd numbered interstates (such as I-65) run primarily north/south.
22 runs in an east-west direction. Odd numbered ones run N-S, even run E-W (generally)
US 1 runs from Key West, Florida (Mile 0) to Fort Kent, Maine, on the Canadian border 2377 miles away. Odd numbered Interstates run north & south. Even numbered ones run east & west.
E-W Interstates and highways are even numbers.
All odd numbered highways run North/South. All even numbered highways run East/West.
Odd-numbered highways in the USA.