There are 75600 permutations.
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If all ten letters are used then it is factorial 10 = 10! = 10x9x8x7x6x5x4x3x2x1 = 3628800
There are 8! = 40320 permutations.
There are 6! = 720 permutations.
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There are 11!/(4!*4!*2!) = 34,650 ways.