If you mean permutations of the letters in the word "obfuscation", the answer is 1,814,400.
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39916800 permutations are possible for the word INFORMATION.
There are 5P3 = 5!/2! = 5*4*3 = 60 permutations.
720
There is only one combination. There are many permutations, though.
8 digits will generate over 40,000 permutations.