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There are 8C6 = 8*7/(2*1) = 28 combinations.
You need to specify how many characters, form the eight, are to be in the combinations. For example, there is only 1 combination of 8 characters.
In what sense? - i dont know, put them in a triangle, in a z-shape, a stright line, a "U" shape...
5 X 4 X 3 X 2 X 1 = 120