Depends on the work you do. For example, say you work at a supermarket, either at a cash register or arranging stuff in the shelves, you would probably not use calculus in your daily work; if you are an economist consultant that has to try to optimize profit for the same supermarket, it is quite possible that you do use calculus.
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It is certainly used in calculus, just as calculus can be used in trigonometry.
I am assuming you understand the distinction between single-variable calculus (calculus of one variable) and multivariable calculus (calculus of several variables). Well, if you know the former, that is highly beneficial because the same techniques are used in the latter -- they are generalized to apply to calculus of n-variables. This is ultimately the goal of single-variable calculus. Why? Well, if you think about it, single-variable is not really applicable. Not many real world phenomena involve one variable. For example, in macroeconomics, GDP = Y is a function of many variables: Consumption (a function of net taxes and income), Investment (a function of real interest rates), Government Spending, and Net Exports. That is, Y=f(C(Y,T), I(r), G, NX). To perform many of the tools of calculus (e.g. finding how Y changes as G increases) to this function, one must know and apply multivariable calculus.
People often divide Calculus into integral and differential calculus. In introductory calculus classes, differential calculus usually involves learning about derivatives, rates of change, max and min and optimization problems and many other topics that use differentiation. Integral calculus deals with antiderivatives or integrals. There are definite and indefinite integrals. These are used in calculating areas under or between curves. They are also used for volumes and length of curves and many other things that involve sums or integrals. There are thousands and thousand of applications of both integral and differential calculus.
In the ancient system of Greek numbers it had the value 5. In calculus it is often used to represent very small values.
pi = 3.14. It is an important and often used metric dating back hundreds of years in algebra and calculus.