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Rabeprazole is a selective and irreversible proton pump inhibitor. Rabeprazole suppresses gastric acid secretion by specific inhibition of the hydrogen-potassium adenosine triphosphatase (H+, K+-ATPase) enzyme system found at the secretory surface of parietal cells. It inhibits the final transport of hydrogen ions (via exchange with potassium ions) into the gastric lumen. Since the H+, K +-ATPase enzyme system is regarded as the acid (proton) pump of the gastric mucosa, rabeprazole is known as a gastric acid pump inhibitor. Rabeprazole does not have anticholinergic or histamine H2-receptor antagonist properties

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Q: Mode of action of Rabeprazole
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What is the difference between Pantoprazole and rabeprazole?

Pantoprazole and rabeprazole are both proton pump inhibitors used to reduce stomach acid production. They have different chemical structures and slightly different mechanisms of action, but they are both effective in treating conditions such as acid reflux and ulcers. The choice between the two drugs is typically based on individual patient response and tolerability.


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