http://wiki.answers.com/Q/Surface_area_is_an_important_factor_in_limiting_cell_growth_because the cell may become too large to take in enough _____food______ and remove enough ____wastes.____
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Because only the surface contacts the fluid, so that's the only place where dissolution can proceed.
Surface size directly affects the possibility for gas exchange. Volume affects how much the cell can contain. If a cell has a large volume and a small surface area, it will be able to keep in water easily. But if it needs outside gas input for its reactions, the small surface area may be a limiting factor.
The surface area is reduced by a factor 4, the volume by a factor 8.
For areas: Square the Scale Factor.
The area changes by the square of the same factor.