14 and 2
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16 and 3
How about: 4+12 = 16
63? But it has more than two one-digit factors.
1, 2, 4, 7, 8, 14, 16, 28, 32, 56, 64, 112, 128, 224, 256, 448, 512, 896, 1792, 3584
The two numbers whose sum is 58 and whose difference is 16 are 21 and 37.