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Severity of disease depends primarily upon these factors. [1] Severity Of Disease Causing Factor Microorganism, chemical toxin, trauma, metabolic disorder, or whatever be the disease causing factor is responsible for severity of disease. Intensity, load, duration of the causative agent determines the severity of disease. Example: If the force of trauma on the sheen bone is very severe the resulting disease would be severe. [2] The Resistance Of The Human Body System. The age, gender, weight, race, comorbid conditions (coexisting diseases), habits (smoking), immunization status, immune status of the body that is afflicted by disease determines severity of disease. Example: A person who has been immunised against typhoid, cholera, diphtheria, pertusis, tetanus (lethal unless you have been immunised by Tetanus Toxoid Vaccination) almost never has severe disease even if the causative organism be in high quantum. [3] Treatment measures. How soon, whether adequate treatment measures have been given is major factor influencing severity of disease. Example: Cancer of cervix, Breast cancer are better managed if diagnosed (Pap smear for early diagnosis of Cervical cancer) and treated correctly in early stage. [4] Unknown factor or Miracle factor. I have no hesitation in saying that severity of disease can suprise all the above three factors and be less or grave. Cause is unknown and may be attributed to luck, grace or divine intervention.

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Q: What is the factor on which severity of a disease depends on?
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