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That depends a lot on how often you may repeat each digit, and what operations are allowed. If you just want to write a four-digit number, using each digit once, start by writing the largest digit on the left, then continue with the second-largest, etc.
Using the digits of 1345678, there are 210 three digit numbers in which no digit is repeated.
The biggest 4 digit number that can be made from using the digits of 850236, using a digit at most once, is 8653.
The idea is to start from the left, and use the smallest digit possible in each case. For instance, the smallest option for the first digit is 2, the smallest option for the second digit is 0, etc.
1324