Five twos.
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-32 = -25The only prime factor of -32 is 2. Negative numbers can't have prime factorizations.
The numbers below are the factor pairs of 4,096 (multiplied together they equal 4,096): (1, 4096) (2, 2048) (4, 1024) (8, 512) (16, 256) (32, 128) (64, 64)
There is no GCF of 32 and 81 because no prime numbers go into either 32 or 81
18
3 and 5. 225 = 3 x 3 x 5 x 5 which can also be written 32 x 52.