How many 16x16 square inch tiles do you need to cover 72 feet?

Answer 1

It is not possible to answer the question because the area to be covered is not specified.

If the area to by covered is 72 feet x 0.25 inches, so that its area is 216 sq inches, then 1 tile should be sufficient.

If the area to be covered is 72 feet by 2.5 inches, then 9 tiles will be enough.

If the area to be covered is 72 feet x 72 feet, then 2916 tiles will be required.

You have not provided all the information required to answer the question properly.