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0000-9999 (10x10x10x10 or 104) = 10,000 possible combinations allowing for repeated digits. If you are not able to repeat digits then it's 10 x 9 x 8 x 7 or 5,040 possible combinations without repeated digits.
Simple enough to solve. The answer is a power of two. Assuming you have two possible digits, say for example, 3 and 4, then you simply have to multiply it by how many numbers you want to get the total number of combinations. Each number can be 3 or 4 in this case, and you have 5 numbers. That's two to the fifth. Five combinations of any two numbers. 2x2x2x2x2. The answer is 32 combinations.
To calculate the number of possible combinations for the number 24680 using each number only once, we can use the formula for permutations. There are 5 numbers to arrange, so the number of permutations is 5! (5 factorial), which is equal to 5 x 4 x 3 x 2 x 1 = 120. Therefore, there are 120 possible combinations for the number 24680 using each number only once.
120 combinations using each digit once per combination. There are 625 combinations if you can repeat the digits.
35,152,000 (assuming that 000 is a valid number, and that no letter combinations are disallowed for offensive connotations.) Also, no letters are disallowed because of possible confusion between letters and numbers eg 0 and O.