Reorder the terms:
-5 + 42y + 27y2
Factor a trinomial.
(-5 + -3y)(1 + -9y)
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(4x - 3y)(16x^2 + 12xy + 9y^2)
n=72 satisfies the relation. 2*72 = 12**2, and 3*72 = 6**3. The only question is whether or not that is the smallest integer that will do so. All perfect squares of which 2n is a factor are of form (2x)**2 = 4x**2, with n= 2x**2. Similarly all perfect cubes of which 3n is a factor are of form (3y)**3 = 27y**3 with n = 9y**3. So, we need integers x and y such that 2x**2 = 9y**3. If the integers x and y are the smallest that satisfy the equation, then we have the smallest n. It doesn't work for y = 1, or any other odd number. If y = 2, n = 72. There is a number x =6 which satisfies the relation. Since y is smallest possible, then n=72 is the smallest positive integer that satisfies the relation.