It depends on how many values each number is capable of having, and if repetition is allowed, and then if order is important. For example, are you rolling dice, picking Lotto balls, BINGO, etc. I am posting a link to a site called MathsIsFun, which has some good information about Combinations and Permutations.
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120
There are a huge number of combinations of 5 numbers when using the numbers 0 through 10. There are 10 to the 5th power combinations of these numbers.
There are 252 combinations.
5
120 WRONG! That is the number of PERMUTATIONS. In the case of combinations, the order of the numbers does not matter, so there is only 1 5-number combination from 5 numbers.